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Women or children that touch skin treated with testosterone products, may develop certain symptoms. Testosterone topical products may harm women and children who touch your skin where it has been applied. Research has shown that testosterone levels play a key role in changing the distribution of fat from subcutaneous to visceral as we age. Usually once daily at the same time either first thing in the morning or at bedtime ensures stable hormone levels in the body. When choosing where to apply hormone-based creams, individual factors must be considered during your consultation with your physician. Repeatedly putting the hormone cream on the same spot can possibly irritate the skin or can create inconsistent absorption due to subtle changes in the skin barrier. Additionally, topical testosterone may not be recommended for males with a history of urinary issues, or for those at high risk for prostate cancer. There are several different types of topical testosterone that are available. The Food and Drug Administration (FDA) has approved topical testosterone in gel form. Your testosterone levels typically peak in early adulthood and slowly decrease with age. Then, apply the cream or gel to clean, dry skin somewhere on your shoulders, upper arms, inner thighs, or stomach. Topical testosterone can cause changes in your lipid (fat) levels in your blood, including cholesterol. Call your health care provider right away if you have any of the following symptoms. Call your health care provider right away if you have any of the following symptoms of liver damage. Liver damage, also called hepatotoxicity, can happen when using topical testosterone. Call your health care provider right away or go to the nearest emergency room if you have any of the following serious symptoms. Use topical testosterone exactly as prescribed. Tell your health care provider right away if you have any of the following symptoms of erythrocytosis or polycythemia. Topical testosterone can also affect your urinary tract and may worsen symptoms of benign prostatic hyperplasia (BPH). Follow the application directions on the package carefully and report any skin reactions to your doctor. Topical testosterone is a treatment for hypogonadism that may occur with age. Testosterone replacement therapy may also be applied to the skin via patch form. The application instructions are the same for both testosterone gels and creams. While not as common as gel versions, testosterone creams may also be sold in specialty pharmacies. Otherwise, the effects of gels vs. creams are not very different. There may be other side effects of topical testosterone that are not listed here. The most common side effects of topical testosterone are listed below. Medicines that contain testosterone (also known as testosterone replacement therapy, or TRT) work by adding more testosterone to a person’s body to help them achieve normal levels. TESTOSTERONE (tes TOS ter one) is used to increase testosterone levels in your body. Some other nations — including the United Kingdom, Australia, New Zealand and South Africa — have approved testosterone products for women. "Part of the confusion with testosterone and estrogen is that we genderize them and call them ‘sex hormones,’" says Dr. Crawford. In adulthood, the typical testosterone level for women is around 40 nanograms per deciliter (ng/dL), though the normal range varies from 15 to 70 ng/dL. Testosterone therapy may be an option for women to help address low libido WebMD does not provide medical advice, diagnosis or treatment. Jessica Migala is a freelance writer specializing in health, nutrition, fitness, and beauty. Contact us at if you see an error. Every article is rigorously reviewed by medical experts to ensure accuracy. We source research from peer-reviewed medical journals, top government agencies, leading academic institutions, and respected advocacy groups. The Edge upholds the highest standards of health journalism. This can increase hemoglobin levels in your blood. Contact your health care provider if you think you are having a side effect of a medicine. Testosterone is a sex hormone that is made naturally in the body.
