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LH tells the testicles to make testosterone, while FSH helps make sperm. Doctors often check hormone levels regularly to see how the body is responding. This combination offers the benefits of TRT while avoiding some of the common drawbacks, especially when it comes to fertility and testicular health. HCG also helps the body keep making sperm, which is important for men who want to stay fertile. HCG acts like LH, keeping the testicles active, supporting sperm production, and preventing shrinkage. Combining TRT with HCG helps the body maintain important natural functions that TRT alone may shut down. Future studies should evaluate changes in hematocrit levels in these patients, as well as the effect that baseline luteinizing hormone may play on response to hCG monotherapy. Our data suggests that hCG can be a safe and efficacious treatment option for patients with symptoms of hypogonadism who do not desire fertility. We found that hCG monotherapy, over an average therapy duration of 6 months, significantly improved testosterone levels in this cohort of men. We hypothesize that hCG monotherapy will be effective at increasing serum testosterone levels and improving symptomatology. Adult-Onset Hypogonadism is defined as having low testosterone in conjunction with clinical signs or symptoms such as low energy, low libido, decreased lean body mass, erectile dysfunction, fatigue, depression, anemia and infertility (3-6). We evaluated patient age, treatment indication, hCG dosage, past medical history, physical exam findings and serum testosterone and gonadotropins before and after therapy. However, it is not uncommon for men to present with signs and symptoms of testosterone deficiency, despite having testosterone levels greater than 300 ng/dL. Shockwave therapy uses low-intensity acoustic waves to stimulate new blood vessel growth and tissue regeneration. When combined with therapies like Sermorelin, HCG and TRT create a well-rounded approach to hormone optimization that supports both short-term performance and long-term health. HCG helps offset these effects by mimicking luteinizing hormone, keeping the testes active and functional. HCG can help prevent this by acting like LH, keeping the testicles active and sperm production going. The exact dose depends on a man’s age, hormone levels, and fertility goals. It is also used for men who notice testicular shrinkage, since that can be a sign that the body has stopped making its own hormones. When these men were given HCG along with their testosterone therapy, most were able to keep normal sperm counts. Research shows that HCG can help protect sperm production during TRT. According to the American Urological Association, hCG is appropriate for those MAABs with testosterone deficiency who also desire to maintain fertility. Pregnancy tests check hCG levels in the urine or blood to determine if a person is pregnant or not. Our easy and secure Labcorp Patient™ account allows you to get lab results, track your health history, manage appointments and pay bills—all in one place. With Labcorp OnDemand, you can purchase the same tests trusted by doctors, directly from Labcorp. From tests you can purchase online to convenient apps, Labcorp is your partner to managing your health. Taking control of your health starts with the right tools. You have the right to ask questions and request health screenings, but you might not know where to begin. Once testosterone levels return to their naturally "low normal," you will start to see the benefits diminish. Because testosterone is such a powerful hormone, ending treatment can adversely affect patients. This intrinsic production contributes other hormones and precursors that are part of the natural testicular output, such as pregnenolone and other prohormones. Sermorelin stimulates your body’s natural growth hormone production, supporting lean muscle, enhanced recovery, improved sleep and greater vitality.